Liver fluke infection in vietnam: A review

Van Anh Thi Tran, Phuc Duc Pham, Dung Trung Do

Abstract


Introduction: Zoonotic trematode infections are an area of the neglected tropical diseases that have become of major interest to public health, including liver fl uke disease caused by Clonorchis, Opisthorchis, Fasciola and Paragonimus. Vietnam is in hot and humid tropics with a high rainfall. These are favorable conditions for the development of intestinal worms, including the liver fl uke. The liver fl uke is widely distributed throughout the country with different prevalence in each region.
Objectives: To summarize existing evidence on liver fl uke and foodborne zoonotic trematode infection, and to highlight the local characteristics of liver fl uke infections, including information on biological features, epidemiology, pathology and policies, and thus giving an appropriate insight into prevention and control of the diseases of liver fl uke and foodborne zoonotic trematodes in Vietnam.
Methods: A systematic literature search was conducted using the PubMed and ScienceDirect databases and data sources of National Institute of Malariology Parasitology and Entomology (NIMPE) in July 2016. The collected documents were summarized and categorized according to each research topic, related to liver fl uke in Vietnam.
Results: Totally, 31 references were included in this review (biological characteristics: 4; epidemiological characteristics: 8; Risk factors: 8; Health impacts of liver fl uke: 7; Prevention and treatment: 4). Most of the studies focused on epidemiological characteristics and risk factors of liver fl uke infection.
Conclusion: In Vietnam, the number of liver fl uke studies and its effects on human health are still limited. Therefore, It’s necessary to conduct further studies on a large scale in the   community to fi nd out the causes, risk factors, high-risk areas, the disease caused by the liver fl uke and the long-term prevention solutions.


Keywords


liver fluke; Clonorchiasis; Opisthorchiasis; Fascioliasis; foodborne zoonotic trematodes; fishborne zoonotic trematodes

Full Text:

PDF

References


Ministry of Health (2004), Decision 1450/2004 / QD-BYT guiding the treatment diagnosed liver fl uke, the lung fl uke, tapeworm and tapeworm larvae disease.

Ministry of Health (2006), Decision No. 3240 / QD / BYT September 13, 2006 on the issuance of “Guidelines for Diagnosis and treatment of liver fl uke disease in humans”.

Cuong, DM (2013), “ The situa on of small liver fl uke infec on and some related factors in Hoa Nghia, Duong Kinh district, Hai Phong, 2013”, Journal of malaria and parasite diseases control, 6 (3): 22-28.

Chuong, NV et al. (2011), A Model of Fasciola control in two communes of Phu Cat District, Binh Dinh Province, Viet Nam, Na onal Ins tute of Malariology Parasitology and Entomology. Report of Parasitology Conference 38th. Episode II - Parasitology - Entomology, Ha Noi.

De, NV (2013), Parasitology in Clinical, Medical Publishing House, Ha Noi.

De, NV(2013), “ A case study of lung fascioliasis for misdiagnosis as cancer “, Y hoc Thanh pho Ho Chi Minh, 17 (1): 130-134.

De, NV et al. (2011), Situa on of liver fl uke infec on on groups diagnosed with liver tumor in hospital in Hanoi in 2006-2010, Report of tại Na onal Scien fi c Conference specialized Malaria - Parasitology - Entomology, Ha Noi.

De, NV and Than, PV (2013), Medical Parasitology., Curriculum for general prac oners, Medical Publishing House, Ha Noi.

Hung, NM and Dung, DT (2011), Preven on of worms in the 2006-2010 period and orienta ons for implemen ng cys cercosis preven on programs, 2011-2015.

Huong, NT (2012), Research on epidemiological characteris cs and eff ec veness of treatment of liver fl uke Trilabendazole in Nghia Son and Tinh Ky, Quang Ngai Province (2008- 2011), Doctoral thesis, Ha Noi.

Huong, NT et al. (2015), Research on assessing large liver fl uke in 4 provinces of Thanh Hoa, Nghe An, Bac Giang, Hoa Binh, 2013-2014, Na onal Ins tute of Malariology Parasitology and Entomology. Report of Na onal Scien fi c Conference specialized Malaria - Parasitology - Entomology, Medical Publishing House, Ha Noi

Lap, TT (2011), Situa on of small liver fl uke infec on and the eff ec veness of interven ons in a coastal commune of Nam Dinh Nam 2007 - 2008, Disserta on in Doctor of Medicine, Thai Binh, 129 pages.

Loi, CB et al. (2007), “ Situa on of intes nal nematode infec on and clonorchis sinensis in Khanh Thuong commune, Ba Vi district, Ha Tay provincce”, Journal of malaria and parasite diseases control, 6: 95-99.

Luc, NK (2010), Study on some characteris cs of liver fl uke infec on (Fasciola spp.) and the eff ec veness of interven ons in Dai Loc District - Quang Nam, Disserta on in Doctor of Medicine, Ha Noi, 163 pages.

Luong, LL and De, NV (2013), “Some characteris cs of hepatobiliary imaging in pa ents with large liver fl uke at the general hospital in Thanh Hoa province in 2011-2012”, Journal of Prac cal Medicine, 884 (10): 13-15.

Ly, ĐTK and Trung, TN (2012), “ Clinical and subclinical characteris cs of 147 cases of liver fl uke in some central provinces 2010-2012”, Journal of Prac cal Medicine 855, 2: 86-91.

Mai, DTT et al. (2014), “ The situa on of small liver fl uke infec on and some related factors in 3 communes in Nga Son District, Thanh Hoa Province, 2011, 2011”, Journal of malaria and parasite diseases control, 1 (8): 49-54.

Minh, DT et al. (2011), Evalua on some risk factors for small liver fl uke infec on in 3 coastal district of nam dinh province, Report of Na onal Ins tute of Malariology Parasitology and Entomology. Report of Parasitology Conference 38th. Episode II - Parasitology - Entomology.

Quang, HH et al. (2008), “ Evalua on of clinical manifesta ons, laboratory fi ndings and imaging diagnos cs in Fasciola pa ents at some central and west highland area, Viet Nam, 2006-2008 “, Y hoc Thanh pho Ho Chi Minh, 12 (4): 11-18.

Son, LT et al. (2013), “ Survey on epidemiological, clinical and paraclinical characteris cs and treatment results of pa ents infected with intes nal parasites a ending the ins tute of malariology - parasitology - entomology in Ho Chi Minh City “, Y hoc Thanh pho Ho Chi Minh, 17 (1): 87-94.

Tuyet, LT and Kham, TQ (2008), “ Situa on of liver fl uke infec on in people in Xuan Chau and Xuan Tien, Xuan Truong District, Nam Dinh Province “, Journal of malaria and parasite diseases control, 3: 87-92.

Van, NV (2012), Situa on of human liver fl uke and eff ec ve interven on measures in communi es in Quang Nam (2009 - 2011), Medical disserta on, Ha Noi, 132 pages.

Ins tute of Malariology Parasitology and Entomology Quy Nhon (2012), Fluke disease transmi ed

through food - one of three tropical diseases neglected (NTDs) is interested in Vietnam by the World Health Organiza on (WHO), 2015, Accessed at:-16-6, Available at: h p://www. impe-qn.org.vn/impe-qn/vn/portal/InfoDetail. jsp?area=58&cat=1174&ID=6043.

Ins tute of Malariology Parasitology and Entomology Quy Nhon (2014), Sharing clinical and treatment of a number of special cases of liver fl uke caused by F. gigan ca, Accessed at: 22-6-2015, Available at: h p://www. impe-qn.org.vn/impe-qn/vn/portal/InfoDetail. jsp?area=58&cat=1174&ID=7042.

Ins tute of Hygience and Public Health (2012), Liver fl uke, Accessed at: 5-9-2015, Available at: h p://www.iph.org.vn/index.php/bnh-truynnhim/251-bnh-san-la-gan-bnh-san-la-gan-nh-clonorchiasis.

Nyindo, M and Lukambagire, AH (2015), “Fascioliasis: An Ongoing Zoono c Trematode Infec on”, BioMed Res Int, 2015: 1-8.

Nguyen, VD and Le, TH (2011), Current status of opisthorchiasis in Vietnam, In Proceedings & Abstracts: 96 Years of Opisthorchiasis, Interna onal Congress of Liver Flukes: 7–8, March 2011, Thailand.

Pilsczek, FH, “Helminthic infec ons mimicking malignancy: A review of published case reports”, J Inf Dev Count, 4: 425-429.

Qian, MB et al. (2012), “The global epidemiology of clonorchiasis and its rela on with cholangiocarcinoma”, Infect Dis Poverty, 1: 1-11.

Sithithaworn, P et al. (2014), “Roles of liver fl uke infec on as risk factor for cholangiocarcinoma”, J Hep Panc Sci, 21: 301-308.

WHO (2010), Working to Overcome the Global Impact of Neglected Tropical Diseases: First WHO Report on Neglected Tropical Diseases, World Health Organiza on.