Current State of Health-Related Cost-Effectiveness Analyses in Vietnam: A Literature Review

My Thi Tuyet Nguyen, Thanh Xuan Nguyen


Introduction: Cost-effectiveness analysis (CEA) is considered as one form of full health economic evaluation, which evaluates both costs and consequences. CEA provides important information for decision makers in choosing optimal options within a given budget. Little is known about CEA in the health sector in Vietnam. Objectives: To describe the current state of health-related CEA studies in Vietnam in terms of quantity and quality and to suggest future directions in this area. Methods: A systematic literature search was conducted on PubMed and Google Scholar databases in July 2014. All found health-related CEA studies in Vietnam were reviewed by two researchers using the Drummond’s checklist. Results: Totally, 18 CEA studies were included, of which 13 evaluated prevention interventions 2 curative procedures, 1 diagnostic procedures, and others (2 studies). Most of the studies used a societal or a healthcare perspective (12 out of 18 studies). 14 out of 18 selected studies showed that it is cost-effective when implementing particular interventions/programs/treatments. Conclusion: In Vietnam, number of health-related CEA studies in PubMed library are still limited and mainly focused on prevention such as vaccines and controlling risk factors. 14 out of 18 selected studies showed that it is cost-effective when implementing the interventions/programs/treatments. More resources should be allocated to this area of research in order to improve the efficiency of health-related policies and decisions.


cost-effectiveness analysis; cost-utility analysis; health; Vietnam

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Tantivess S. Policy making and roles of health technology assessment. Journal of the Medical Association of Thailand = Chotmaihet thangphaet. 2008 Jun;91 Suppl 2:S88-99.

Tran BX, Ohinmaa A, Duong AT, et al. Cost-effectiveness of integrating methadone maintenance and antiretroviral treatment for HIV-positive drug users in Vietnam's injection-driven HIV epidemics. Drug and Alcohol Dependence. 2012;125(3):260-6.

Kim S-Y, Goldie SJ, Salomon JA. Cost-effectiveness of Rotavirus vaccination in Vietnam. BMC Public Health. 2009;9(1):29.

Fischer TK, Anh DD, Antil L, et al. Health care costs of diarrheal disease and estimates of the cost-effectiveness of rotavirus vaccination in Vietnam. The Journal of infectious diseases. 2005;192(10):1720-6.

Higashi H, Truong KD, Barendregt JJ, et al. Cost effectiveness of tobacco control policies in Vietnam: the case of population-level interventions. Applied health economics and health policy. 2011;9(3):183-96.

Suba EJ, Nguyen CH, Nguyen BD, Raab SS, Viet/American Cervical Cancer Prevention P. De novo establishment and cost-effectiveness of Papanicolaou cytology screening services in the Socialist Republic of Vietnam. Cancer. 2001;91(5):928-39.

Kim JJ, Kobus KE, Diaz M, O'Shea M, Van Minh H, Goldie SJ. Exploring the cost-effectiveness of HPV vaccination in Vietnam: Insights for evidence-based cervical cancer prevention policy. Vaccine. 2008;26(32):4015-24.

Casey GJ, Sartori D, Horton SE, et al. Weekly iron-folic acid supplementation with regular deworming is cost-effective in preventing anaemia in women of reproductive age in Vietnam. PLoS One. 2011;6(9):e23723.

Nguyen LH, Laohasiriwong W, Stewart JF, Wright P, Nguyen YTB, Coyte PC. Cost-Effectiveness Analysis of a Screening Program for Breast Cancer in Vietnam. Value in Health Regional Issues. 2013;2(1):21-8.

World Health Organization. The Global Burden of Disease 2004 update; 2008.

Nguyen Phuong Hoa, Chalapati Rao, Damian G Hoy, Nguyen Duc Hinh, Nguyen Thi Kim Chuc, Duc Anh Ngo. Mortality measures from sample-based surveillance: evidence of the epidemiological transition in Viet Nam. World Health Organization. 2012.

Ministry of Health - Vietnam Administration of HIV/AIDS control. Vietnam HIV/AIDS estimates and projections 2007-2012; 2009.

Tran Tuan Anh, Hoang Van Minh. Assessing health economic training and demand in universities and research institutions in Vietnam. Journal of Practical Medicine. 2012;3.